Method for non-invasive wrinkle removal and skin treatment

ABSTRACT

A method for the treatment of wrinkles on human skin, by stimulating collagen growth beneath the epidermis layer, comprising the steps of: arranging a pulsed dye laser generator in light communication with a pulsed dye laser delivery device. The pulsed dye laser delivery device is applied against tissue having wrinkles. The pulsed dye laser generator generates a pulsed dye laser light. A pulsed dye laser light from the pulsed dye laser delivery device is directed onto the tissue, to reach hemoglobin in a collagen layer up to about 1.2 mm. beneath the surface of the tissue to effect growth changes therein.

BACKGROUND OF THE INVENTION

1. Field of The Invention

The present invention relates to the field of resurfacing skin, orwrinkle removal using laser radiation for treatment of underlying layersof skin.

2. Prior Art

Plastic surgeons, dermatologists and their patients continually searchfor new and approved methods for treating the effects of an aging skin.Historically, the treatment of facial wrinkles was primarilyaccomplished with the use of chemical peels or dermabrasion. The use ofchemical peels has fallen out of favor, because it is difficult toaccurately control and predict the depth of tissue injury after suchpeels are applied. Deeper chemical peels in particle have an increasedrisk of hypopigmentation and scarring. Such injury to the top layer ofskin, which would be peeled away, would permit new cells to supposedlyrejuvenate the skin. A less expensive way of injuring the outer layer ofthe skin is the utilization of an abrasive wheel, to rough off the skinlayer. This method is not well controlled, and is very difficultespecially around the eyelids.

Laser skin resurfacing began with a carbon dioxide laser. The carbondioxide laser energy is absorbed by tissue water causing vaporization ofthe outer skin layer. Carbon dioxide lasers have been utilized forapproximately 3 decades. However it has only been the past few yearsthat these lasers have been arranged to remove only thin tissue layerswith minimal heat damage to the surrounding skin. While carbon dioxidelasers may remove about 150 microns of skin, that skin may take a monthor more to heal under such a procedure.

Er:YAG lasers have been utilized to ablate even thinner layers of tissuethan carbon dioxide layers. However they lack the coagulationcharacteristics and thus allow more bleeding than a carbon dioxide laserduring use.

Non-ablative skin resurfacing, is a methodology which does not take thetop layer of skin off, but which shrinks the collagen under the skin,and modifies that collagen, so that the wrinkled skin appears to befill-in by the collagen modified beneath the skin. This methodologyhowever, has a low efficiency, and a cryogen coolant must be sprayed onto the skin so as to minimize damaging the top or upper layer thereofand also to minimize pain generation. The “fluence” or energy densityused is greater than 10 joules per square centimeter and to be moreeffective this fluence often reaches 30 Joules per square centimeter.This level of energy often causes pain and epidermal damage.

It is an object of the present invention to improve upon theshortcomings of the prior art.

It is yet a further object of the present invention to provide a skinresurfacing laser treatment, which is nonablative, and minimizes anypain to the patient being treated.

It is yet still a further object of the present invention, to provide anew method to stimulate the collagen beneath the skin surface, toimprove the surface appearance from beneath that surface of skin of thepatient.

BRIEF SUMMARY OF THE INVENTION

The present invention comprises a system and methodology for noninvasivewrinkle removal for the modification of collagen beneath the epidermis.The laser system of the present invention, in a preferred embodiment,utilizes a pulsed dye laser having a deep penetrating wavelength ofabout 585 nanometers (nm) laser, so as to target hemoglobin of blood inthe skin tissue. This particular laser energy is absorbed by thehemoglobin. The heat is generated in the skin area up to about 1 mm indepth and typically uses energy of less than 5 Joules per square cm,having a preferred target spot size of about 10 mm diameter.

The pulsed dye laser apparatus of the present invention includes ahandpiece connected by an optical fiber or wave guide, critically, to apulsed dye laser generator device.

The handpiece focuses, through a plurality of lenses, the pulsed dyelaser light from the pulsed dye laser generator, onto the spot of about10 mm in diameter, so as to stimulate new collagen growth beneath theepidermis without injuring the surrounding structures.

In the preferred embodiment of the present invention, the pulse widthhas a range of 150 microseconds to about 1500 microseconds with apreferred width of about 450 microseconds. The wavelength of the pulseddye laser apparatus of the present invention lies in a range of about570 nanometers to about 650 nanometers, with a preferred wavelength ofabout 585 nanometers. The present invention provides a preferred fluenceof less than 5 Joules per square cm., and preferably 3 Joules per squarecm at a 10-millimeter diameter skin treatment spot.

By treating the skin to this low fluence pulsed dye laser light,collagen may be stimulated to regenerate and “fill in” valleys ofwrinkles for a younger more clearer skin.

Thus what has been shown is a new method of stimulating modification ofthe collagen layer at a depth of at least about 1 mm to about 1.2 mmbeneath the skin surface, utilizing a low energy level of less than 5Joules per square cm., in a manner not appreciated by the prior art.

The invention thus comprises a method for the treatment of wrinkles onhuman skin, by stimulating collagen growth beneath the epidermis layer,comprising the steps of: arranging a pulsed dye laser generator in lightcommunication with a pulsed dye laser delivery device; applying saidpulsed dye laser delivery device against tissue having wrinkles;generating a pulsed dye laser light by said pulsed dye laser; anddirecting said pulsed dye laser light from said pulsed dye laserdelivery device onto said tissue, to reach hemoglobin in a collagenlayer beneath the surface of said tissue. The method includes the stepsof: tuning said pulsed dye laser to deliver a laser light at awavelength having a range of from about 570 nanometers to about 650nanometers, and adjusting said range of pulsed dye laser light generatedto a wavelength of about 585 nanometers. The pulsed dye laser has apulse width in a range of from about 150 microseconds to about 1500microseconds. Preferably the pulsed dye laser has a pulse width of about450 microseconds. The method included the pulsed dye laser light beingdirected at the tissue at a target spot diameter of about 10 mm. Themethod includes maintaining a fluence of the pulsed dye laser light ofless than 5 Joules per square cm.

BRIEF DESCRIPTION OF THE DRAWINGS

The objects and advantages of the present invention will become moreapparent, when viewed in conjunction with the following drawings, inwhich:

FIG. 1 is a schematic representation of the laser apparatus of thepresent invention, as it is applied to a layer of skin; and

FIG. 2 is a graph showing the absorption characteristics of certain bodytissue chromophors versus laser wavelength.

DESCRIPTION OF THE PREFERRED EMBODIMENTS

Referring now to the drawings in detail, and particularly to FIG. 1,there is shown the present invention, which comprises a system 10, andmethodology for nonivasive wrinkle removal for the modification ofcollagen beneath the epidermis. The laser system 10 of the presentinvention, in a preferred embodiment, utilizes a pulsed dye laser 12having a deep tissue-penetrating wavelength of about 585 nanometers (nm)laser, so as to target hemoglobin “H” of blood in the skin tissue “T”.The preferred pulsed dye laser 12 generates a particular laserwavelength energy of 585 nanometers, which is absorbed by the hemoglobin“H”. The heat is generated in the skin tissue “T” area up to about 1 mmin depth and typically uses energy of less than 5 Joules per square cm,having a preferred target spot size “S” of about 10 mm diameter circleor larger.

The pulsed dye laser apparatus 12 of the present invention includes ahandpiece 14 connected by an optical fiber or wave guide 16, critically,to a pulsed dye laser generator for generating the particular wavelengthand fluence of the present invention.

The handpiece 14 focuses, through a plurality of lenses 20 22 and 22 24,the pulsed dye laser light “L” from the pulsed dye laser generator 12,onto the spot “S” of about 10 mm in diameter or larger, so as tostimulate new collagen growth beneath the epidermis “E”.

In the preferred embodiment of the present invention, the pulse widthhas a range of 150 microseconds to about 1500 microseconds with apreferred width of about 450 microseconds. The wavelength of the pulseddye laser apparatus 12 of the present invention lies in a range of about570 nanometers to about 650 nanometers, with a preferred wavelength ofabout 585 nanometers. The present invention provides a preferred fluenceof less than 5 Joules per square cm., and preferably 3 Joules per squarecm at a 10-millimeter diameter skin treatment spot “S”.

By treating the skin “T” to this low fluence pulsed dye laser light “L”,collagen beneath the epidermis, that is below about 0.06 mm. beneath thesurface may be stimulated to regenerate and “fill in” valleys ofwrinkles for a younger more clearer skin.

Thus what has been shown is a new method of stimulating modification ofthe collagen layer at a depth of up to about 1 mm to about 1.2 mmbeneath the skin surface, utilizing a low energy level of less than 5Joules per square cm., in a manner not appreciated by the prior art.

1. A method for the treatment of wrinkles on human skin, by stimulatingcollagen growth beneath the epidermis layer, comprising the steps of:arranging a pulsed dye laser generator in light communication with apulsed dye laser delivery device; applying said pulsed dye laserdelivery device against tissue having wrinkles; generating a pulsed dyelaser light by said pulsed dye laser; and directing said pulsed dyelaser light from said pulsed dye laser delivery device onto said tissue,to reach hemoglobin in a collagen layer beneath the surface of saidtissue; adjusting said range of pulsed dye laser light generated to awavelength of about 585 nanometers; generating said pulsed dye laser ata pulse width of about 450 microseconds; directing said pulsed dye laserlight at the tissue at a target spot diameter of about 10-mm; andmaintaining a fluence of said pulsed dye laser light of less than 5Joules per square cm.
 2. A method for the treatment of wrinkles on humanskin, by stimulating collagen growth beneath the epidermis layer,comprising the steps of: arranging a pulsed dye laser generator in lightcommunication with a pulsed dye laser delivery device; applying saidpulsed dye laser delivery device against tissue having wrinkles;generating a pulsed dye laser light by said pulsed dye laser; anddirecting said pulsed dye laser light from said pulsed dye laserdelivery device onto said tissue, to reach hemoglobin in a collagenlayer beneath the surface of said tissue; and tuning said pulsed dyelaser to deliver a laser light at a wavelength having a range of about585 nanometers; generating said pulsed dye laser at a pulse width ofabout 450 microseconds; and energizing said collagen down to a depth ofabout 1.0-mm to about 1.2 mm. below the surface of the skin by saidpulsed dye laser.
 3. A method for the treatment of wrinkles on humanskin, by stimulating collagen growth beneath the epidermis layer,comprising the steps of: arranging a pulsed dye laser generator in lightcommunication with a pulsed dye laser delivery device; applying thepulsed dye laser delivery device against tissue having wrinkles;generating a laser light pulse with the pulsed dye laser generator, thelaser light pulse having a wavelength in a range of about 570 nanometersto about 650 nanometers, a pulse width in a range of 150 microseconds toabout 1500 microseconds, and a fluence of less than about 5 Joules percm ² ; and directing the laser light pulse from the pulsed dye laserdelivery device onto the tissue, to reach hemoglobin in a collagen layerbeneath the surface of the tissue.
 4. The method of claim 3, wherein thelaser light pulse energizes the collagen down to a depth of about 1.0 mmto about 1.2 mm below the surface of the skin.
 5. The method of claim 3,wherein the pulsed dye laser delivery device comprises a handpiececonnected by an optical fiber or waveguide to the pulse dye lasergenerator.
 6. The method of claim 3, wherein the laser light pulse has awavelength of about 585 nanometers.
 7. The method of claim 3, whereinthe laser light pulse has a pulse duration of about 450 microseconds. 8.The method of claim 3, wherein the laser light pulse has a fluence ofabout 3 Joules per cm² .